Dr. Leon Buffaloe, MD, Internist

Dr. Leon Buffaloe, MD

Internist

‍114 B Hospital Drive
Simpsonville, SC 29681

Overall rating

Top reviews

Dr. Buffaloe is the best doctor in all of Greenville County. He takes his time with you and makes sure he has all of your questions answered before you leave. I feel so comfortable talking to him about any concerns I have. I am soShow more thankful to have a Christian doctor attending to my medical needs. His staff is awesome too. They are all so friendly and accommodating. If you are looking for the best medical staff, look no more. I highly recommend Grace Internal Medicine.

Cathy B. • July 20, 2026

Dr Buffaloe saw me as an add on with severe left shoulder pain, the pain was on going for 4 weeks. I found him to be thorough, compassionate and careful and complete in his exam. He took time to explain his findings. He treated itShow more and wants to see me back for re check! I am grateful to be his patient.

Michele E. • July 28, 2026

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Dr. Leon Buffaloe, MD?


About Dr. Leon Buffaloe, MD

Dr. Leon Buffaloe, Jr. was born in Washington, DC and raised in Prince George’s County, Maryland. At 18, he left home to serve his country as an Army Combat Medic. During 12 years of active duty, Dr. Buffaloe served in Operation Desert Storm, Operation Restore Hope, as well as during the Iraq War. After his tour to Somalia, he was accepted into the Army’s Licensed Practical Nurse Program and continued working across various areas of Nursing.

Dr. Buffaloe obtained a degree with Cum Laude honors in Biological Studies from the University of South Carolina in 2004 and went on to graduate from the University’s School of Medicine in 2008.

After graduating and completing his residency at Palmetto Health Richland—now PRISMA Health Richland—he went to work as a physician with SELF Regional in Laurens, SC and eventually moved to Simpsonville to help open a clinic for PRISMA Health Upstate. Dr. Buffaloe felt led to take his 30+ years of healthcare experience to build Grace Internal Medicine, an independent practice with an affiliate partner in MUSC (Medical University of South Carolina).

With a comfortable and approachable environment, Grace Internal Medicine welcomes community members from all over the Upstate, all of whom can be expect to be treated with the utmost respect. Whether you are a longtime patient, employee, or new to Grace Internal Medicine, Dr. Buffaloe and his team are committed to making a difference in your healthcare journey.

Meeting his wife while on tour in Honduras in 1999, Army Surgical technologist, Asante, now Family Medicine Physician, have four kids Dominique, Nicholas, Leon III, and Naomi - along with a beagle named CJ! In his downtime, Dr. Buffaloe enjoys time with his family, and working in his church.


Location

Grace Internal Medicine

‍114 B Hospital Drive
Simpsonville, SC, 29681


More About Dr. Leon Buffaloe, MD

NPI Number

1366603391

Provider's Gender

Male


Reviews

4.93
314 Reviews

Excellent provider

Reginald S. • July 29, 2026

Dr Buffaloe saw me as an add on with severe left shoulder pain, the pain was on going for 4 weeks. I found him to be thorough, compassionate and careful and complete in his exam. He took time to explain his findings. He treated it and wants to see me back for re check! I am grateful to be his patient.

Michele E. • July 28, 2026

Have been going to Dr. Buffalo for years would not change doctors for anything he is a very good doctor easy to talk to very polite, knowledgeable.

Barbara G. • July 24, 2026

Doctor buffaloe is a excellent doctor? Very professional very knowledgeable he takes time to find out your concerns and help you with them i will recommend him to anybody.

William N. • July 23, 2026

Dr. Buffaloe is the best doctor in all of Greenville County. He takes his time with you and makes sure he has all of your questions answered before you leave. I feel so comfortable talking to him about any concerns I have. I am so thankful to have a Christian doctor attending to my medical needs. His staff is awesome too. They are all so friendly and accommodating. If you are looking for the best medical staff, look no more. I highly recommend Grace Internal Medicine.

Cathy B. • July 20, 2026

Dr. Buffaloe is one of the most caring doctor ever!! He is differently always there for his patients!!

Robert P. • July 16, 2026

Great experience with the staff and Dr.Buffalo

Timothy B. • July 15, 2026

Always does a great job. I would refer my family and friends to you. Dr Buffaloe listen to your problems and he gives you the best advice.

Martha J. • July 14, 2026

Dr. Buffaloe has been my guy for about 10yrs. First class.

Ralph S. • July 13, 2026

Great facility and people

Vincent D. • July 09, 2026

Good

Stefan W. • July 07, 2026

Great Doctor. He’s patient and try’s to know what the patience needs are. If it is out of his jurisdiction, he will give a referral. He’s solution driven, but will work with the patient where they are.

Sheila L. • June 28, 2026

Great

Felix H. • June 17, 2026

He is professional, very detail and explanatory, checks all the boxes and ask you for questions or concerns.

Elois W. • June 17, 2026

Front desk ladies very friendly and helpful. Nurses very friendly and helpful. Dr Buffaloe spent all the time with me that was needed. Highly recommend.

Kenneth B. • June 16, 2026

As always I am very happy with the services provided at Grace Internal Medicine. I appreciate the care that Dr. Buffaloe provides.

Walter S. • June 07, 2026

Always shows himself friendly and shows care. 20 years Dr. Buffalo has been my primary care doctor.

Jeff W. • June 07, 2026

Experience is really good with the medical center and the people are really nice there.

Peggy W. • June 04, 2026

Dr. Buffaloe and the Grace Internal Medicine staff are very professional and thorough.

Vincent M. • June 04, 2026

Wait was little, long but I was not in a big hurry.

Mackie W. • June 03, 2026

Dr buffaloes really great dr. He always listen to his patience and he don't rush with them he will always be my dr. Maggie reed

Maggie R. • June 03, 2026

Excellent customer care

Clarence K. • May 28, 2026

Dr. Buffalo took his time explaining what he was going to do and why. He ensured that I didn’t have any questions or concerns. I did not feel rushed in anyway during my visit.

Atrez F. • May 18, 2026

Excellent service as always!!.

Robbie E. • May 15, 2026

Dr Buffaloe takes his time and listens to what you have to say. He doesn't rush and is considerate of your time and needs

Kelly A. • May 13, 2026

The Dr listened to my concerns and made suggestions I could agree with and seemed very concerned

Patricia O. • May 11, 2026

Very good

Yvonne M. • May 07, 2026

Very good

James P. • May 05, 2026

I like the friendly atmosphere. Everyone seems friendly. The doctor seems professional, concerned and knowledgeable about each situation.

David E. • April 30, 2026

Excellent Service

James S. • April 29, 2026

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